The prostate well being index (PHI) is a blood take a look at that extra precisely assesses the danger of prostate most cancers than a conventional PSA take a look at. The PHI combines three totally different PSA assessments to create one danger rating. It might scale back the necessity for biopsies in people who find themselves at decrease danger for most cancers.
A PHI take a look at makes use of three totally different types of the prostate-specific antigen (PSA), a protein your prostate makes that may develop into elevated you probably have circumstances like an enlarged prostate, prostate an infection, or prostate most cancers. These three kinds embody:
- Complete PSA: The full stage of PSA in your blood
- Free PSA: The portion of PSA that’s not hooked up to proteins in your blood
- p2PSA: A variation of PSA which may be particular to prostate most cancers
The PHI combines the measurements in a system to supply one rating. It provides a extra correct illustration of prostate most cancers danger in comparison with the standard complete PSA take a look at.
The PHI take a look at produces a single rating starting from 0-55+ that may reveal details about your prostate most cancers danger. Increased scores and decrease scores could each reveal totally different info.
A larger rating (above 35) signifies a better likelihood of prostate most cancers that wants therapy. The take a look at shouldn’t be diagnostic, although—a prostate biopsy is important for a definitive prognosis. When you have a barely excessive rating, your healthcare suppliers may look into your different prostate most cancers danger components earlier than figuring out the subsequent steps.
A decrease rating (beneath 35) suggests a decrease danger of prostate most cancers that requires therapy. When you have a decrease PHI rating, healthcare suppliers could select to watch you over time fairly than recommending a biopsy.
The prostate well being index supplies a number of advantages over the standard complete PSA take a look at. These embody:
- Accuracy: The full PSA take a look at cannot differentiate among the many potential causes of an elevated PSA stage. The PHI’s mixture of three variations of PSA makes it extra particular in detecting prostate most cancers.
- Decreased biopsies: As a result of it is extra particular, PHI assessments scale back the necessity for pointless prostate biopsies, sparing the potential prices, discomfort, and different problems of a biopsy.
- Early most cancers detection: Prostate most cancers could not trigger signs till it has reached a complicated stage. PIH is beneficial within the early detection of prostate most cancers, particularly circumstances that require therapy.
It is essential for people who find themselves at a better danger of prostate most cancers to contemplate getting the PHI take a look at. Discuss to a healthcare supplier about your danger, which can be larger in case you:
- Have a household historical past of prostate most cancers
- Are 50 years or older
- Are Black
- Have identified genetic mutations of the genes BRCA1 or BRCA2
Additionally, males with barely larger PSA ranges of 4-10—generally known as a diagnostic grey zone—can endure the take a look at to substantiate whether or not their PSA ranges are seemingly larger resulting from most cancers or one other prostate situation.
The prostate well being index is an easy blood take a look at. A healthcare supplier could ask you to sit down comfortably in a chair. In some circumstances, they might additionally ask you to lie down. Then, you’ll be able to anticipate the blood drawing course of to contain these steps:
- The healthcare supplier cleans the realm with an antiseptic (germ-killing) resolution.
- They put an elastic band in your higher arm to assist the realm swell with blood.
- They insert a needle right into a vein in your arm to gather blood in an hermetic vial or tube hooked up to the needle.
- They take away the needle and band out of your arm and apply a cotton pad or bandage to the needle website.
The take a look at normally takes place at a diagnostic laboratory or your healthcare supplier’s clinic. The price of the take a look at varies, however normally ranges between $35-$370. You possibly can discuss to your medical health insurance supplier, you probably have one, to assist decide whether or not they’ll cowl the price of the take a look at.
The prostate well being index (PHI) is a blood take a look at for prostate most cancers screening. By combining measures of three totally different variations of prostate-specific antigen (PSA), it presents higher accuracy, reduces the necessity for pointless biopsies, and may also help within the early detection of prostate most cancers that wants therapy.