During the last 12 months, I’ve labored to carry the general public’s consideration to dimethyl sulfoxide (DMSO), a forgotten pure remedy which quickly treats a variety of situations and that many research have proven is extraordinarily secure (offered it is used appropriately). Most significantly (because of the 1994 DSHEA act which ended many years of FDA persecution towards pure therapies) DMSO is now available.
Since I imagine DMSO has immense potential to supply the medical group and particular person sufferers, I’ve diligently labored to compile proof that greatest helps its rediscovery. As such, all through this collection, I’ve offered 1000’s of research that DMSO successfully treats:
• Strokes, paralysis, and lots of different neurological or circulatory issues (mentioned right here).
• Power ache and tissue accidents, corresponding to sprains, burns, and non-healing wounds (mentioned right here).
• Quite a few autoimmune and contractile issues (mentioned right here).
• Head situations, corresponding to tinnitus, imaginative and prescient loss, dental issues, and sinusitis (mentioned right here).
• Inner organ ailments, corresponding to pancreatitis, infertility, liver cirrhosis, and endometriosis (mentioned right here).
• Pores and skin situations, corresponding to varicose veins, pimples, hair loss, ulcers and pores and skin most cancers (mentioned right here).
• Many various cancers (mentioned right here).
• Lung issues, together with bronchial asthma, COPD, pulmonary fibrosis, and cystic fibrosis (mentioned right here).
• Infections, together with persistent bacterial infections, herpes, and shingles (mentioned right here).
DMSO Mixture Therapies
DMSO’s capacity to deal with a variety of diseases outcomes from its having quite a lot of extremely uncommon properties that seem to handle the foundation causes of illness (e.g., it dramatically improves circulation). One in all DMSO’s most noteworthy properties is its capacity to reinforce the consequences of different substances, which in lots of circumstances makes it doable to surmount main dilemmas historically seen with these therapies.
DMSO’s distinctive capacity to operate as a car is because of the truth that it will probably go by organic membranes with out damaging them,1 so as soon as it contacts the pores and skin, it quickly spreads all through the physique.2 On the similar time, concurrently it readily dissolves most substances and is ready to carry them with it into the physique. That is very helpful because it lets you:
• Apply a medicine topically or orally that will sometimes require an IV or injection.
• Make medication change into rather more potent and in a position to deal with situations that in any other case is not going to reply to (e.g., these mixtures can penetrate and deal with antibiotic resistant micro organism or chemotherapy resistant cancers).
• Permit decrease doses of a drug for use, which are sometimes a lot much less poisonous and in lots of circumstances, counteract the toxicity of the blended medicine (as DMSO protects tissue from harm) — all of which make it extremely helpful for decreasing the hurt of chemotherapy.
Notice: Whereas DMSO can’t be patented, mixtures can. As such, whereas DMSO alone is “unsafe” “ineffective” and “unproven” many “secure and efficient” DMSO pharmaceutical mixtures exist, together with many accepted by the FDA.
Likewise, when DMSO is mixed with quite a lot of pure therapies, as:
• In lots of circumstances the place DMSO alone doesn’t work for a situation (which DMSO is thought to enhance), a mixture remedy will.
• Whereas DMSO has quite a lot of optimistic pharmaceutical synergies, it seems to work greatest when mixed with pure therapies.
Notice: Pure substances are typically much less poisonous than prescription drugs and thus a lot much less prone to be dangerous as soon as potentiated with DMSO. Nonetheless, it’s nonetheless essential to grasp tips on how to put together these mixtures (mentioned right here) safely.
• Many have discovered that combining DMSO with their favourite pure therapies has allowed them to take medical care into their very own arms and “be their very own physician.”
Pure Mixture Research
An in depth physique of literature exists that corroborates DMSO’s therapeutic synergy with prescription drugs. Many research have additionally proven the therapeutic advantage of pure DMSO mixtures.
Notice: Many accepted DMSO preparations additionally include pure substances that improve DMSO’s results (corresponding to dexpanthenol, menthol, camphor, lavandin, lavender oil, coriander oil, arnica, potassium iodide, and capsicum).
• Chinese language herbs — In China, many promising DMSO natural preparations have been studied (e.g., one successfully handled post-herpetic neuralgia in 31 sufferers).3 These embrace:
◦In rats with Alzheimer’s illness, DMSO and Ginkgo biloba extract (GBE), administered for 14 days, improved studying and reminiscence.4
◦DMSO and purple gromwell successfully handled viral warts.5
◦In mice with cervical carcinoma, remedy with 50 mg/kg DMSO mixed with 20 mg/kg Zhenhuang injection prolonged survival by 65.81% to 69.83% in ascitic tumors and inhibited strong tumor development by 60.83% to 68.33%, considerably outperforming both alone.6
◦DMSO together with a knotweed natural ointment, demonstrated important anti-inflammatory results in rats.7
Notice: Many research have proven DMSO enhances the absorption of plant extracts and the penetration of natural ointments (e.g., for ginseng8,9,10).
• Nutraceuticals — Vitamin C has been mixed with DMSO to deal with quite a lot of situations:
◦A 2022 randomized trial of 25 sufferers (with 28 confirmed basal cell cancers), investigators discovered when it was mixed with 95% DMSO and utilized topically twice a day, after 8 weeks, 86.7% of the cancers had disappeared solely.11 In distinction, after 8 weeks of 5% imiquimod (customary remedy), solely 57.1% had disappeared.
Antioxidants have additionally been repeatedly used with DMSO to guard tissue from harm:
◦DMSO, ascorbic acid, glutamine, hydrocortisone succinate, and pentoxifylline protected the jejunal (intestinal) lining of horses from its blood provide being quickly reduce off.12
◦In rabbits, IV DMSO protected their kidneys from having their blood provide reduce off, with a fair larger impact seen when N-Acetylcysteine was infused concurrently.13
◦A 1983 research confirmed that the rise in blood circulation DMSO created for scleroderma sufferers was enormously enhanced with vitamin B3.14
• Pure antimicrobials — Topical DMSO with iodine has been proven to deal with quite a lot of infections:
◦In 58 sufferers, destructive stress wound remedy, DMSO, and povidone iodine (PVP-I) was discovered to be an efficient remedy for persistent purulent wounds, trophic ulcers with atherosclerotic lesions of the vessels of the extremities, and diabetic angiopathy.15
◦DMSO and PVP-I, with out uncomfortable side effects, have efficiently handled molluscum contagiosum (e.g., within the groin of a 14-month outdated boy16 and a 63-year outdated man17).
◦A DMSO, silver ion, and iodine formulation had a 90% to 95% success price in treating purulent-septic ailments, hoof harm, and mastitis (the place it didn’t impair milk manufacturing and had no toxicity).18
Notice: DMSO, and silver nanoparticles have been additionally discovered to be an efficient remedy for serous mastitis in cows.19,20
Fungal infections additionally reply to those mixtures:
◦DMSO blended with quite a lot of totally different plant extracts was extremely efficient at inhibiting the expansion of resistant Candida infections remoted from sufferers with mouth cancers.21
◦DMSO with meals grade vinegar was discovered to be an efficient remedy for 406 sufferers with fungal athlete’s foot (59% DMSO and 41% vinegar given 3 to 4 occasions a day for 3 to five days)22 and 100 sufferers with jock itch (40% DMSO 60% vinegar).23
Many different infections additionally reply to those mixtures:
◦A 2023 medical trial gave an oral DMSO spray containing zinc iodide, ginger extract, propolis extract, and xylitol to sufferers with delicate or reasonable COVID-19.24 In comparison with placebo, this remedy brought about important enhancements in medical signs, restoration time, and viral clearance.
◦DMSO has additionally been mixed with enzymes to deal with actinomycosis, meningitis or meningoencephalitis (from a viral respiratory an infection) or suppurative wounds,25,26,27 and with a (innocent) antiparasitic fungus to deal with ear infections.28
Notice: DMSO additionally considerably elevated the flexibility of Annona muricata seed extracts to eradicate mosquitoes within the water.29
• Pure dental therapies — In dentistry, DMSO reduces irritation inside tooth (pulpitis) and gums (periodontitis), helps eradicate the micro organism inflicting that irritation, improves blood circulation to tooth, and assists with therapeutic tooth. Many pure substances have been used for this:
◦50% DMSO and 1 mg/ml oleanolic acid (which is discovered in lots of crops together with olives30) in 30 extracted human tooth with enterococcus faecalis infections quickly decreased micro organism ranges, inside 24 hours fully eliminating them, with the mixture being stronger than both alone.31,32,33
◦DMSO, alone or mixed with lysozyme (an antimicrobial exercise), successfully handled acute serous restricted pulpitis in 95.6% of 120 tooth instantly after remedy, with 93.1% success at 3 months and 82.9% at 24 months.34
Notice: 15% DMSO blended with a natural extract additionally handled periodontal illness.35
◦In sufferers with deep caries and early pulpitis, a 20% DMSO and calcium hydroxide mixture used as a pulp-capping remedy considerably decreased irritation and improved outcomes in comparison with conventional strategies.36
◦DMSO in a gel with 10% glucosamine hydrochloride, nettle juice, and Kalanchoe juice successfully handled periodontitis in animals, decreasing irritation and dashing tissue restore.37
• Different head situations:
◦DMSO plus short-acting insulin and 5% calcium pantothenate (B5) safely handled 42 sufferers ages 23 to 62 with persistent parenchymatous parotitis (irritation of the parotid gland).38
◦Sjögren’s syndrome is kind of tough to deal with. In a single research, DMSO alone offered important enchancment which was additional enhanced by vitamin C.39
◦A wide range of DMSO functions enhance tinnitus and in a single research, a mixture spray containing circulation selling brokers like capsicum (and lidocaine) handled tinnitus.
• Wound therapeutic:
◦In mice with second-degree burn wounds, DMSO, collagen, and dextran accelerated therapeutic and decreased irritation.40
◦DMSO blended with linethol (a flaxseed focus with anti-inflammatory, regenerative, and wound-healing properties) handled burns.41
◦DMSO and Brazilian inexperienced propolis successfully decreased irritation and accelerated surgical wound therapeutic in animals and eradicated the necessity for oral drugs.42
Notice: As talked about above, DMSO silver mixtures additionally improve wound therapeutic.
• Different pure most cancers mixtures — Many different pure therapies have been mixed with DMSO to deal with most cancers. For instance, many research have discovered that infusing it with baking soda (sodium bicarbonate) could be very useful for decreasing most cancers signs:
◦A 2011 research discovered it considerably benefited sufferers with metastatic prostate most cancers:43
◦A 2014 research of 9 sufferers with superior biliary adenocarcinomas discovered the identical:44
◦A 2011 research of 26 sufferers with extreme refractory ache from superior cancers discovered it was an efficient technique of ache management that additionally improved the sufferers’ high quality of life, decreased the uncomfortable side effects of chemotherapy, and probably elevated their size of survival.45
DMSO has been extensively proven to suppress most cancers development and trigger most cancers cells to distinguish (revert again to regular cells). A couple of research have assessed this with DMSO mixtures:
◦Alpha-lipoic acid was discovered to considerably improve DMSO’s capacity to distinguish mouse embryonic carcinoma P19 cells, however to not induce differentiation with out DMSO.46
◦Retinoic acid (a vitamin A metabolite) has additionally proven promise for inducing most cancers differentiation, works synergistically with DMSO47,48,49 and makes use of a special differentiating pathway than DMSO.50,51
◦In human ovarian most cancers cells (COC1), DMSO and retinoic acid considerably inhibited cell proliferation and induced differentiation.52
◦A 1969 research discovered that DMSO, when mixed with warmth and vitamin A, selectively focused most cancers cells (and facilitated the discharge of lysosomal enzymes).53
◦In mice with pores and skin most cancers grafts, topical DMSO and vitamin E blended with cabazitaxel suppressed tumor development by 50% in comparison with controls.54
◦A 2023 research discovered that fatty acids remoted from the urine of wholesome cows and blended with DMSO have been an efficient remedy towards breast most cancers cells.55
◦A 2018 research discovered that DMSO and a plant extract selectively arrested cell development and induced cell loss of life of colon most cancers cells.56
Lastly, in a number of the most cancers research that demonstrated DMSO enhanced chemotherapy success, pure therapies have been additionally integrated. For instance, a 1975 research of 65 sufferers with incurable cancers (most of whom had acquired typical therapies) discovered {that a} low dose of cyclophosphamide blended in DMSO with GABA, GABOB, and acetylglutamine cured 57 of them.57
• Different pure mixtures:
◦In rabbits, DMSO protects coronary heart tissue that has misplaced its blood provide from dying, and this safety was enhanced with the simultaneous administration of hydrogen peroxide.58 In devascularized pores and skin flaps, DMSO alone prevented carbon dioxide ranges from growing, and when hydrogen peroxide was added, tissue oxygen ranges then elevated.59
◦A 1980 research gave 129 newborns with osteomyelitis (bone infections) DMSO and hyperbaric oxygen remedy, which improved their normal situation, normalized serum laboratory values, decreased bone destruction, and accelerated bone regeneration.60 Equivalent outcomes have been achieved in a 1978 research of acute and persistent osteomyelitis,61 a 1979 research of 43 kids with persistent osteomyelitis,62 and a 1981 research of 54 kids with acute septic osteomyelitis.63
◦In 38 sufferers with sturdy physique odors, along with a DMSO aluminum chloride mixture, 40% urea in 70% DMSO resolution successfully decreased underarm odor.64
Notice: People have additionally reported utilizing DMSO (alone) as a extremely efficient deodorant.
Frequent Pure DMSO Combos
The security and efficacy of DMSO have impressed a big do-it-yourself group, notably inside Germany, to discover a variety of pure DMSO mixtures. Presently, I do know of round 120 mixtures which have repeatedly benefited sufferers. Nonetheless, as an virtually infinite quantity exists (that could possibly be examined on ailments all through the physique), many outstanding ones stay undiscovered.
Because of this, many various mixtures have been extensively explored, which have been efficiently used to deal with a variety of situations. These embrace:
• Service oils (e.g., coconut oil) — When DMSO is chronically used, it will probably typically dehydrate the pores and skin. Many people discover they’ve a greater response to DMSO inside a service oil or aloe vera, notably when making pure cosmetics.
• Important oils (e.g., lavender or tea tree) — These topical mixtures enormously improve the identified results of the oils, lots of that are used for infections, ache, or different musculoskeletal situations.
• Botanicals (e.g., arnica, CBD oil, or turmeric) — These mixtures have a variety of makes use of, notably therapeutic harm and ache, pores and skin situations, and treating neurological or cardiovascular points.
• Nutraceuticals (e.g., vitamin C, vitamin B12, or MSM) — DMSO’s potentiation and bypassing of requiring injection enormously enhances the identified features of many dietary supplements. These mixtures are regularly used to treatment osteoarthritis, listening to loss, lack of scent, and tinnitus, and for particular ailments like prostate enlargement, Parkinson’s, cataracts, glaucoma, COPD, and bronchial asthma, and cussed infections.
• Minerals (e.g., iodine and magnesium) — Mostly used for musculoskeletal functions, eliminating infections all through the physique, and treating glandular points within the thyroid, prostate, and breast.
• Pure metabolites (e.g., hyaluronic or lactic acid) — Many have outstanding restorative capability and are generally used for beauty functions (e.g., scars, varicose veins, cellulite or pores and skin rejuvenation) together with many complicated issues (e.g., neurodegenerative ailments, most cancers or insulin resistance).
• Amino acids and neurotransmitters (e.g., GABA) — These are most identified for treating Down Syndrome and developmental delays, and are used for insomnia, anxiousness, neurological well being, eye well being, tissue restore, and joint points.
• Oxidative therapies (e.g., chlorine dioxide, hydrogen peroxide or Artemisia Annua) — These are extraordinarily widespread for treating native infections (e.g., dental ones), persistent infections (e.g., Lyme or EBV) and most cancers.
• Dyes — DMSO mixed with hematoxylin is a remarkably efficient (and innocent) most cancers remedy, resulting in the identification of different dyes which can be additionally potent most cancers therapies together with DMSO.
• Chelating and detoxifying brokers (e.g., EDTA or cilantro) — DMSO dramatically will increase the efficacy of chelating brokers (by permitting them to succeed in deeper within the physique) whereas concurrently decreasing the detoxing reactions extra delicate sufferers expertise.
Notice: Many different therapies (e.g., acupuncture, hypnosis, bodily remedy, osteopathy, and meditation) have been reported to change into rather more efficient together with DMSO, in lots of circumstances permitting therapeutic breakthroughs to occur.
Conclusion
The outstanding potential of DMSO alone or together with different therapies represents a paradigm shift in how we method pure therapeutic and wellness. What we have found by 1000’s of research and numerous affected person experiences is that DMSO would not simply deal with signs — it seems to handle basic therapeutic mechanisms on the mobile degree, making a basis for the physique’s personal restorative processes to flourish.
The fantastic thing about these pure mixtures lies not solely of their therapeutic efficacy however of their accessibility. Not like complicated pharmaceutical interventions that require specialised medical amenities and intensive oversight, many of those DMSO mixtures might be safely ready and used at dwelling, empowering people to reclaim their well being.
Briefly, the mixing of DMSO mixture therapies into healthcare holds large promise, and on account of MAHA, we’re lucky to be at a time in historical past the place these forgotten therapies can lastly flourish. The way forward for medication could be discovered on this outstanding solvent’s capacity to unlock the therapeutic potential that has at all times existed inside nature — we merely wanted the appropriate key to entry it.
Writer’s Notice: That is an abridged model of an extended article which matches into a lot larger element on what every of the pure DMSO mixtures can do and tips on how to put together them at dwelling. That article, together with assets and protocols for acquiring and utilizing DMSO might be learn right here. Moreover, a companion article explaining how DMSO interacts with a variety of drugs and the synergistic pharmaceutical mixtures which have been found might be learn right here.
A Notice from Dr. Mercola Concerning the Writer
A Midwestern Physician (AMD) is a board-certified doctor from the Midwest and a longtime reader of Mercola.com. I admire AMD’s distinctive perception on a variety of matters and am grateful to share it. I additionally respect AMD’s want to stay nameless since AMD remains to be on the entrance traces treating sufferers. To seek out extra of AMD’s work, be sure you try The Forgotten Facet of Drugs on Substack.
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