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Treating SIBO Holistically Helps Patients Feel Better, New Study Finds

by Dr. Mercola
June 7, 2025
in Health
Reading Time: 11 mins read
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Small intestinal bacterial overgrowth, or SIBO, is greater than only a intestine imbalance — it is a signal your digestive system has misplaced its rhythm. Whereas most individuals consider it as a bacterial downside, it is actually a deeper challenge with vitality, motility and terrain. In different phrases, SIBO exhibits up when your intestine slows down, your defenses weaken and micro organism migrate into areas they do not belong.

The signs, like bloating, gasoline, constipation or diarrhea, and even meals intolerance, are irritating sufficient. However what’s worse is how usually the situation will get misdiagnosed, mismanaged or misunderstood altogether.

Too usually, the main target is on wiping out micro organism fairly than asking why these micro organism took over within the first place. Antibiotics are handed out as first-line remedy, but they usually depart sufferers feeling worse — triggering yeast overgrowth and additional disrupting the intestine ecosystem.

What many practitioners miss is that SIBO tends to develop in folks with low abdomen acid, sluggish intestine motility or thyroid-related slowdowns that allow issues stagnate. Add metabolic stress, iron overload or hormone imbalances to the combination, and also you’re coping with an ideal storm, not simply of micro organism however of terrain gone haywire. That is why short-term methods do not work. They deal with signs whereas the basis causes stay.

A brand new real-world research out of Valencia, Spain, presents one thing totally different.1 As a substitute of relying solely on lab markers, the researchers requested a greater query: How do folks really really feel after remedy? And that is the place the solutions begin to get attention-grabbing.

Recognizing SIBO as a Actual, Treatable Situation Improves Outcomes

A scientific research printed in Vitamins examined how a complete remedy strategy improved the lives of individuals recognized with SIBO.2 The researchers targeted on whether or not sufferers felt higher after 90 days, not simply whether or not their lab checks modified.

They assessed each breath take a look at outcomes and self-reported well being scores. Breath checks are generally used to detect irregular gasoline ranges, like hydrogen and methane, that sign bacterial overgrowth within the small gut. This was one of many largest research of its sort, particularly analyzing real-life affected person experiences.

• The research adopted adults with confirmed SIBO — The 179 sufferers had a confirmed prognosis of hydrogen- or methane-dominant SIBO. Most had been middle-aged (common age 45.7) and 82.7% had been girls. All members obtained tailor-made remedy involving remedy, herbs, probiotics and a nutritionist-guided weight loss plan. The researchers wished to see how this multi-layered strategy impacted not simply take a look at outcomes, however folks’s day-to-day high quality of life.

• Over 70% of sufferers felt higher by the tip of remedy — Greater than 7 in 10 sufferers — 72.6% — reported important enhancements in signs after three months. In distinction, solely 41.3% had “normalized” breath take a look at outcomes. Folks felt reduction from bloating, ache, stool points and digestive misery even when gasoline ranges remained elevated.

• Modifications had been seen rapidly and continued to enhance over time — Many sufferers began feeling higher inside 30 days, however probably the most constant progress occurred between 30 and 90 days. This means that therapeutic your intestine and rebalancing your microbiome takes time. It additionally reinforces the necessity for constant follow-through. Individuals who caught with the protocol noticed the best enhancements by the three-month mark.

• SIBO with constipation confirmed barely stronger symptom reduction — Folks with methane-type SIBO, which is usually related to constipation, tended to reply barely higher than these with hydrogen-dominant SIBO, which often causes diarrhea and gasoline.

Whereas each teams improved, 73.2% of methane SIBO sufferers noticed reduction, in comparison with 71.4% within the hydrogen group. The remedy’s potential to revive extra common bowel patterns performed a significant function on this enchancment.

Multi-Pronged Methods Improved Digestion, Temper and Resilience

Sufferers reported higher emotional steadiness, psychological readability, sleep high quality and vitality following remedy. Key intestine signs, together with bloating, constipation, diarrhea, urgency and post-meal fullness additionally improved, and higher perform in areas like mobility, self-care and participation in regular each day actions was reported. Stool high quality improved as properly. Many shifted from exhausting or unfastened stools to extra regular stool consistency by day 90.

• Greater preliminary self-rated well being predicted higher outcomes — Sufferers who believed they had been in higher well being at first had a a lot increased probability of seeing important symptom enchancment. That discovering speaks to the ability of self-perception and mindset in restoration. If you belief your physique and really feel able to getting higher, your odds go up.

• SIBO remedy linked to mind and temper enhancements — Folks usually report higher temper and fewer signs of tension and despair after SIBO remedy. That is tied to the gut-brain axis, the communication freeway between your intestine and mind. Irritation, poor motility and stress disrupt this pathway, so restoring intestine well being naturally helps psychological readability and emotional stability.

• Therapies probably labored by restoring intestine barrier and microbial steadiness — Researchers imagine that utilizing glutamine, probiotics and prebiotics supported intestine barrier integrity and lowered irritation. Natural antimicrobials (like berberine, peppermint and oregano oil) focused overgrowth with out destroying helpful species. These mechanisms assist reshape the ecosystem of your small gut, permitting good micro organism to thrive and limiting the survival of problematic ones.

• The intestine’s therapeutic course of took time and a number of methods — This wasn’t a one-size-fits-all or quick-fix mannequin. Every affected person obtained steerage from a nutritionist, together with scientific supervision. Weight-reduction plan was custom-made, herbs had been chosen based mostly on gasoline sort and reintroduction phases had been paced step by step. This multi-layered strategy allowed for higher tolerance and extra lasting outcomes.

Why Chopping Carbs and Utilizing Antibiotics Typically Make SIBO Worse

In case you’ve been informed to chop carbs to regulate bacterial overgrowth, it is time to rethink that strategy. Ravenous your intestine reduces signs for some time, nevertheless it will not repair the issue — and in the long term, it should gradual your metabolism, impair intestine motility and shrink your meals tolerance. That is not therapeutic. That is buying and selling one type of dysfunction for an additional.

• SIBO is not brought on by consuming carbs — It is a metabolic breakdown. When your digestive system is underpowered — when your thyroid is sluggish, your abdomen acid is low or your intestine motility is compromised — micro organism that ought to keep in your colon creep into your small gut and multiply. That is when signs like bloating, discomfort, gasoline and constipation take over.

• Antibiotics aren’t the answer — In case you’ve already been by means of a spherical of antibiotics like rifaximin for SIBO, you may be coping with one thing else, too — candida overgrowth. Western drugs usually overlooks the truth that antibiotics do not simply kill micro organism. They disrupt your whole intestine ecosystem.

Yeast like Candida albicans are left behind, untouched and able to unfold. They transfer quick. And once you’ve lower carbs within the hopes of “ravenous” the unhealthy micro organism, candida does not die. It adapts. It transforms into an invasive, aggressive type that damages your intestine lining and creates a second layer of dysfunction — fungal overgrowth layered on high of bacterial imbalance.

The best way to Repair SIBO Naturally

To really recuperate, you should tackle each issues — SIBO and candida overgrowth — on the similar time, and you should begin by rebuilding your metabolism and immune defenses. This is the place I might begin:

1. Keep away from fiber and complicated carbs till your signs ease — If in case you have SIBO, your intestine is usually overwhelmed by micro organism which have migrated into your small gut, the place they do not belong. Many wholesome meals — particularly these wealthy in fiber or starch — grow to be problematic on this state. That is as a result of they ferment too rapidly or aren’t damaged down correctly, which feeds the overgrowth and results in gasoline, bloating, discomfort and irritation.

Various kinds of carbs have an effect on your intestine otherwise. Soluble fibers, as an illustration, are usually tolerated higher than insoluble ones. Soluble fiber ferments extra slowly, giving your digestive system extra time to course of it. However in case you’re coping with lively signs, even these make issues worse. Insoluble fibers are sometimes particularly irritating — they bulk up stool and velocity up digestion, which exacerbates signs like diarrhea, urgency or cramping.

Your greatest technique early on is to restrict set off meals. Give attention to these which are best to digest and least prone to gasoline bacterial overgrowth. This contains tender fruits with out skins and well-cooked white rice.

Keep away from beans, uncooked greens, complete grains and fibrous fruits or greens till your system stabilizes. As your digestion improves, you will step by step regain tolerance. The bottom line is listening to your physique and increasing your weight loss plan slowly. Transfer from easy, low-fiber carbs to extra fibrous complete meals as soon as your intestine is calm.

2. Feed your intestine cells with out feeding dangerous micro organism — Your small gut is designed for absorption — not fermentation. However when micro organism overgrow on this space, even nutritious carbs grow to be gasoline for the mistaken microbes. That is why choosing the proper carbohydrates is crucial, particularly throughout early restoration.

Easy carbs which are quickly absorbed in your higher gut are typically higher tolerated by these with SIBO. These carbs do not attain your colon, so that they’re much less prone to feed dangerous oxygen-tolerant micro organism that produce toxins like endotoxin. The truth is, by avoiding fermentation, they assist decrease endotoxin publicity and cut back irritation all through your intestine lining.

On the similar time, this strategy provides your cells a clear supply of vitality to restore tissue and enhance motility. Begin with carbs like white rice, fruit juices with pulp or complete fruits. As soon as your signs enhance and your digestion stabilizes, start introducing mild advanced carbs like well-cooked squash or peeled potatoes. From there, step by step reintroduce extra fibrous choices like root greens, and at last beans and complete grains.

The aim is not to limit carbohydrates perpetually. It is to offer your intestine time to rebuild and your mitochondria the vitality they should restore digestive tissues. As your intestine well being improves, your potential to digest and profit from extra advanced carbs will return — with out flaring signs or fueling overgrowth. In the end, as a substitute of proscribing carbs, deal with consuming 250 grams of the fitting sorts each day.

3. Tackle the terrain that allowed overgrowth within the first place — SIBO and candida do not occur in a vacuum. They present up when your physique turns into a secure haven for them. Candida, as an illustration, thrives in estrogen-dominant environments. It additionally feeds on extra iron.

Balancing hormones, avoiding xenoestrogens in microplastics and preserving your iron ranges in examine are all a part of this therapeutic equation. And in case your thyroid is underactive, every little thing — from motility to immune protection — slows down. That is why I usually advocate checking thyroid perform in case you’ve been caught within the SIBO-candida loop.

4. Monitor your physique temperature to maintain candida in examine — Low physique temperature provides candida precisely what it needs — a cooler, extra hospitable atmosphere the place it might probably unfold. Fungal pathogens like candida thrive when your temperature dips under regular whereas increased physique temperatures assist suppress fungal development and hold your inside defenses sturdy. In case your daytime temp constantly falls under 98.6 levels F, you are giving candida room to take maintain and multiply.

5. Cease treating signs in isolation and begin rebuilding your inside atmosphere — You do not want a low-carb protocol or a protracted course of antibiotics. You want a metabolic basis sturdy sufficient to withstand bacterial and fungal overgrowth within the first place.

Which means fueling constantly with the fitting wholesome carbs, avoiding environmental chemical compounds, reducing stress and giving your physique the uncooked supplies it must hold your intestine ecosystem secure. As soon as your terrain improves, the unhealthy micro organism cease thriving — with out you needing to assault them head-on with antibiotics.

This strategy is gradual, regular and rooted in restore, not restriction. In case you’ve been caught within the cycle of antibiotics, antimicrobials and elimination diets, it is time to shift your technique. You are not damaged; you are simply under-fueled and over-stressed. Begin by fixing your metabolism, and your intestine will comply with.

In case you’re coping with each SIBO and candida, the answer is not to choose one to battle — it is to shift the terrain they’re dwelling in. A well-fed, high-functioning intestine does not permit overgrowth to take maintain. That is the actual aim right here. And it is completely inside your attain.

FAQs About SIBO

Q: What’s SIBO and why is it usually misdiagnosed?

A: SIBO occurs when micro organism that belong in your colon migrate into your small gut. This results in bloating, gasoline, belly ache and irregular bowel habits like constipation or diarrhea. It is often misdiagnosed as a result of a lot of its signs mimic different digestive issues, and customary breath checks usually give inconsistent outcomes.

Many medical doctors deal with it as a easy bacterial downside, when in actuality, it is a signal of metabolic and digestive dysfunction that enables overgrowth to occur within the first place.

Q: What makes this research’s findings so necessary for folks with SIBO?

A: The Vitamins research redefines what success seems like in SIBO remedy. As a substitute of chasing excellent lab outcomes, it targeted on whether or not folks really felt higher after individualized remedy, together with weight loss plan adjustments, herbs, probiotics and drugs. They usually did — greater than 70% of members skilled reduction from bloating, stool points, fatigue and digestive misery, even when their breath checks nonetheless confirmed elevated gasoline.

Q: Why do antibiotics and low-carb diets usually make SIBO worse?

A: Antibiotics like rifaximin briefly cut back bacterial overgrowth however usually trigger collateral harm by disrupting your intestine’s microbial steadiness. This opens the door for fungal pathogens like candida to take over. In the meantime, chopping carbs in an effort to “starve” micro organism weakens your metabolism, slows intestine motility and stresses your immune defenses — situations that make each SIBO and candida worse, not higher.

Q: What is the hyperlink between SIBO and candida overgrowth?

A: When antibiotics knock out micro organism, yeast like Candida albicans thrive within the disrupted atmosphere. Candida turns into extra aggressive below stress, particularly when carbs are restricted. It shifts into an invasive type that damages your intestine lining and worsens irritation. Many individuals unknowingly find yourself with each SIBO and candida — two overlapping imbalances that require a twin strategy to resolve.

Q: What’s one of the best ways to heal from SIBO and candida overgrowth long-term?

A: Lasting restoration begins by restoring your metabolic well being and inside terrain. The aim is not to struggle microbes — it is to make your intestine a spot the place overgrowth cannot take maintain. That features:

• Supporting intestine restore with easy carbs like complete fruit and white rice earlier than step by step reintroducing extra fiber

• Avoiding hormone, low physique temperature and iron imbalances that feed candida

• Ditching elimination diets in favor of nutrient-dense, metabolism-supporting meals

• Bettering thyroid perform to activate intestine defenses

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