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7 Possible Side Effects of Creatine

by Sherri Gordon
November 9, 2025
in Health
Reading Time: 3 mins read
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Whereas creatine is taken into account a secure and well-researched complement, it does include potential unintended effects. When taking greater than the really useful 3 to five grams a day—reminiscent of throughout the loading section—you could expertise abdomen upset, water retention, and slight weight acquire. With extended use at excessive ranges, you could possibly additionally expertise muscle cramps, electrolyte imbalances, kidney points, and elevated liver enzymes.

Taking greater doses of creatine could trigger digestive upset. Researchers have discovered that taking about 10 grams per day could set off gastrointestinal (GI) signs like abdomen upset, diarrhea, bloating, and nausea.

This facet impact is much less more likely to happen with customary doses. In case you are taking greater doses of creatine and have digestive points, attempt decreasing the quantity you’re taking.

Taking greater doses of creatine throughout a loading section, or about 20 grams a day for 5 to seven days, could trigger you to retain water. Usually, this water weight is short-term and can go away after you start the upkeep section of three to five grams every day.

If you wish to keep away from water retention, persist with the really useful dose of three to five grams per day and skip a loading section. You’ll nonetheless expertise constructive outcomes—simply not as shortly.

It’s not unusual to realize slightly weight when taking creatine. A few of this weight acquire is short-term and associated to water retention. Your weight could enhance by two to 6 kilos throughout a loading section. This weight acquire is normally short-term and can go away as soon as you turn to a upkeep dose.

You might also acquire a small quantity of weight as a consequence of a rise in muscle mass. This muscle weight acquire improves your physique composition and helps with fats loss, and shouldn’t be a trigger for concern.

As a result of creatine is filtered by way of your kidneys, there’s a threat of kidney points, particularly in case you have present kidney circumstances. For those who do have pre-existing kidney illness, don’t complement with creatine with out speaking with a healthcare supplier.

You probably have regular kidney perform, you may possible use creatine with none points. The rise in creatinine ranges is normally solely short-term, however it could possibly nonetheless be useful to speak with a healthcare supplier.

Some analysis has discovered that supplementing with creatine can cut back the chance of muscle accidents. Nonetheless, different research have discovered that creatine supplementation could result in elevated muscle cramping or muscle strains.

The important thing to decreasing these dangers is to remain hydrated, take note of your physique, and make changes. Some muscle cramping could also be brought on by overuse or a scarcity of water.

Creatine causes water retention and pulls water away from the remainder of your physique. If you don’t keep properly hydrated whereas supplementing with creatine, this may increasingly trigger an electrolyte imbalance. Monitor your water consumption, particularly when you reside in a sizzling local weather otherwise you ceaselessly do high-intensity workout routines.

Though uncommon, there have been some studies of elevated liver enzymes from taking creatine. In case you are taking one other treatment or complement metabolized by your liver, or in case you have an present liver situation, discuss to a healthcare supplier earlier than supplementing with creatine.



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